Abstract：Tsutsugamushi disease, also known as scrub typhus, is a zoonosis caused by Orientia tsutsugamushi, with rats as the main sources of infection and chigger mites as the only medium of transmission, and has no effective vaccines. Tsutsugamushi disease can be divided into summer, autumn and winter types according to seasons in China, while the summer type is characterized by strong virulence, typical and severe symptoms, high rates of misdiagnosis and mortality. The summer type of tsutsugamushi disease is distributed in the south of 31°N in China, with the epidemic time from June to August, and the cases are predominantly females, farmers and people at ages of over 40 years. Affected by natural environment, social and economic factors, the epidemic areas and the number of cases of summer type of tsutsugamushi disease are increasing continuously. Based on publications pertaining to the epidemiology of summer type of tsutsugamushi disease in China from 1960 to 2023, this review summarizes the mechanism of transmission, epidemiological characteristics and influencing factors, so as to provide the basis for prevention and control of summer type of tsutsugamushi disease in China.
明小力, 杨晓庆, 周瑜, 任天广. 我国夏季型恙虫病流行病学研究进展[J]. 预防医学, 2023, 35(9): 778-780.
MING Xiaoli, YANG Xiaoqing, ZHOU Yu, REN Tianguang. Research progress on the epidemiology of tsutsugamushi disease of summer type in China. Preventive Medicine, 2023, 35(9): 778-780.
[1] 于恩庶,陈香蕊,吴光华,等.中国恙虫病研究[M].香港:亚洲医药出版社,2000. [2] 李贵昌,王玉姣,岳玉娟,等.我国恙虫病夏季型和秋季型疫区划分研究[J].中国媒介生物学及控制杂志,2019,30(3):233-236. [3] 张之伦,于长水.天津市恙虫病的发现及国内外研究概况[J].疾病监测,1996,11(3):103-106. [4] 张嘉溪,谭盛葵.恙虫病流行病学研究新进展[J].中国热带医学,2022,22(3):274-278. [5] 韩腾伟,刘菁,洪荣涛,等.福建省2010—2013年恙虫病流行特征分析[J].海峡预防医学杂志,2015,21(6):8-10. [6] 刘艳慧,李乔玄,景钦隆,等.广州市2006—2015年恙虫病疫情时空分布特征[J].中国媒介生物学及控制杂志,2017,28(4):336-339. [7] 王珊珊,黄佳亮,苏建新,等.中国南海重要岛屿恙虫病疫源地特点调查[J].中华流行病学杂志,2007,28(10):996-999. [8] 王玉姣. 北京市平谷区恙虫病自然疫源地研究[D].佳木斯:佳木斯大学,2020. [9] 周培盛. 广西西南地区恙虫病自然疫源地调查[J].中国媒介生物学及控制杂志,1991,2(3):206-209. [10] 周淑姮,韩腾伟,王加熊,等.福建省部分地区野栖鼠体表寄生恙螨的物种多样性调查[J].中国人兽共患病学报,2021,37(6):511-519. [11] 雷永良,陈秀英,柳付明,等.浙江省丽水市监测点鼠类恙虫病东方体的检测[J].疾病监测,2011,26(2):118-119. [12] 孙笑梅. 云南省部分鼠科小兽恙螨寄生状况研究[D].大理:大理学院,2012. [13] 黎家灿. 中国恙螨[M].广州:广东科技出版社,1997. [14] 李文,李贵昌,刘小波,等.恙虫病流行特征及影响因素研究进展[J].中国媒介生物学及控制杂志,2020,31(6):738-743. [15] 李光密,张新雄,邓德生.恙虫病新媒介吉首纤恙螨的发现及流行病学研究[J].中华流行病学杂志,1989,10(增刊3):109-113. [16] JEONG H W,CHOI Y K,BAEK Y H,et al.Phylogenetic analysis of the 56-kDa type-specific protein genes of Orientia tsutsugamushi in Central Korea[J].J Korean Med Sci,2012,27(11):1315-1319. [17] 张萌,王显军,赵仲堂.中国恙虫病流行态势及预防控制[J].中华流行病学杂志,2011,32(4):419-423. [18] 徐秉锟,陈心陶.地里红恙虫的发育和温度之关系的研究[J].微生物学报,1960,8(1):1-7. [19] DING F Y,WANG Q,HAO M M,et al.Climate drives the spatiotemporal dynamics of scrub typhus in China[J].Glob Chang Biol,28(22):6618-6628. [20] 曾志伟,韩腾伟,刘维俊,等.2020年福建省恙虫病流行特征分析[J].热带医学杂志,2022,22(9):1295-1298. [21] 李柏成,朱洁云,王霄玲,等.广西某医院2014—2018年恙虫病致急性肾损伤临床对照分析[J].中华疾病控制杂志,2019,23(9):1132-1136. [22] 孙烨. 我国恙虫病地方性流行南北异质性比较研究[D].北京:中国人民解放军军事医学科学院,2016. [23] 廖勇,黄仁发,胡晓军,等.2006—2017年江西省恙虫病流行病学分析[J].现代预防医学,2019,46(7):1167-1170. [24] 张云,吴光华,邓小昭,等.东南沿海地区地理景观与恙虫病流行特征关系[J].中国公共卫生,2010,26(2):174-175. [25] PENG P Y,XU L,WANG G X,et al.Epidemiological characteristics and spatiotemporal patterns of scrub typhus in Yunnan Province from 2006 to 2017[J].Sci Rep,2022,12(1):2985. [26] 秦瑶,张伦,张瑶,等.2016—2020年四川省恙虫病流行特征分析[J].预防医学情报杂志,2022,38(10):1329-1333. [27] XIN H L,SUN J L,YU J X,et al.Spatiotemporal and demographic characteristics of scrub typhus in Southwest China,2006-2017:an analysis of population-based surveillance data[J].Transbound Emerg Dis,2020,67(4):1585-1594. [28] 谢晓菲,王高玉,黄艺,等.中国恙虫病流行及临床研究进展(2010—2020)[J/OL].海南医学院学报,2022[2023-08-17].https://doi.org/10.13210/j.cnki.jhmu.20220802.001. [29] YAO H W,WANG Y X,MI X M,et al.The scrub typhus in mainland China:spatiotemporal expansion and risk prediction underpinned by complex factors[J].Emerg Microbes Infect,2019,8(1):909-919. [30] HE J Y,WANG Y,LIU P,et al.Co-effects of global climatic dynamics and local climatic factors on scrub typhus in mainland China based on a nine-year time-frequency analysis[J/OL].One Health,2022,15[2023-08-17].https://doi.org/10.1016/j.onehlt.2022.100446. [31] HAN L,SUN Z B,LI Z M,et al.Impacts of meteorological factors on the risk of scrub typhus in China,from 2006 to 2020:a multicenter retrospective study[J/OL].Front Microbiol,2023,14[2023-08-17].https://doi.org/10.3389/fmicb.2023.1118001. [32] 吕艳. 中国西南地区地里纤恙螨等重要恙螨分布规律研究[D].贵阳:贵州大学,2021. [33] PENG P Y,GUO X G,JIN D C,et al.Landscapes with different biodiversity influence distribution of small mammals and their ectoparasitic chigger mites:a comparative study from southwest China[J/OL].PLoS One,2018,13(1)[2023-08-17].https://doi.org/10.1371/journal.pone.0189987. [34] TRAUB R,WISSEMAN JR CL.The ecology of chigger-borne rickettsiosis(scrub typhus)[J].J Med Entomol,1974,11(3):237-303. [35] LV Y,GUO X G,JIN D C.Research progress on Leptotrombidium deliense[J].Korean J Parasitol,2018,56(4):313-324. [36] YANG S,LIU X B,GAO Y,et al.Spatiotemporal dynamics of scrub typhus in Jiangxi Province,China,from2006 to 2018[J/OL].Int J Environ Res Public Health,2021,18(9)[2023-08-17].https://doi.org/10.3390/ijerph18094599. [37] 吴义城,李青华,张文义,等.恙虫病流行特征及危险因素研究进展[J].公共卫生与预防医学,2015,26(2):70-74. [38] MCMAHON B J,MORAND S,GRAY J S.Ecosystem change and zoonoses in the Anthropocene[J].Zoonoses Public Health,2018,65(7):755-765. [39] 卫宪钰,欧琳琳,张文义,等.中国大陆恙虫病流行特征、危险因素及预测研究进展[J].寄生虫与医学昆虫学报,2022,29(1):60-66.
